Dr. Dennis R. LaJeunesse

Assistant Professor of Biology

Curriculum Vita
Room 231 Eberhart Building
336.256.1071 (Phone)

Drlajeun@uncg.edu

LAJEUNESSE HOME

EDUCATION
Post-doctoral fellowship, Duke University, 1996-2000
Ph.D. Biology, The Johns Hopkins University, 1991-1995
B.A. cum laude Classics, Lehigh University, 1985-1989
B.A. cum laude Biology, Lehigh University, 1985-1989

GRANTS
DOD Neurofibromatosis Program New Investigator Award. “Genetic and molecular characterization of Drosophila brakeless: a novel modifier of Merlin phenotypes.” $371,040/3 years.

GRANT HISTORY
NRSA postdoctoral fellowship 1997-2000
Neurofibromatosis Foundation Young Investigator Fellow, 1996-1997
Duke University Hargit Fellowship 1995-1996

PUBLICATIONS
Tripoulas, N. A., E. Hersperger, D. LaJeunesse, and A. Shearn. (1994) Molecular genetic analysis of the Drosophila melanogaster gene absent, small and homeotic 1.Genetics 137, 1027-1038.

LaJeunesse, D. R., and A. Shearn. (1995) The trans-regulation of the thoracic homeotic gene of the ANTP-C and BX-C by trithorax group genes, absent small and homeotic 1 and 2. Mechanisms of Development 53: 123-139.

Tripoulas*, N., D. LaJeunesse*, J. Gildea, A. Shearn. (1996) The Drosophila ash1 gene product, which is localized at specific sites on polytene chromosomes, contains a SET domain and a PHD finger. Genetics 143: 913-928. *equal authorship.

LaJeunesse, D. R., and A. Shearn. (1996) Enhancer of zeste/polycombeotic: a Polycomb group gene or a trithorax group gene? Development 122: 2189-2197.

Fehon, R. G., T. Oren, D. R. LaJeunesse, T. Melby, and B. M. McCartney.(1997) Isolation of mutations in the Drosophila homologues of the human Neurofibromatosis-2 and yeast CDC42 genes using a simple and efficient reverse-genetic method. Genetics 146: 246-252.

Fehon, R. G., D. R. LaJeunesse, R. Lamb, B. M. McCartney, L. Schweitzer, and R. E. Ward. (1997) Functional studies of the protein 4.1 family of junctional proteins in Drosophila. Soc. Gen. Physiol. Ser. 52: 149-159.

LaJeunesse, D. R., B. M. McCartney and R.G. Fehon. (1998) A Structural Analysis of Drosophila Merlin reveals Functional Domains Important for Growth and Subcellular Localization. Journal of Cell Biology 141:1589-1599.

McCartney, B. M., Kulikaukas, R. M., LaJeunesse, D. L., and Fehon R.G. The Neurofibromatosis-2 homologue Merlin and the Drosophila tumor suppressor expanded function together to regulate cell proliferation and differentiation. Development.

LaJeunesse, D. R., McCartney, B.M., and Fehon R.G. A systematic screen for second site modifiers of Merlin phenotypes reveals novel candidates involved in Neurofibromatosis-2 gene function. Genetics.158: 485-497

Adamson, A. L., LaJeunesse, D. R., and Kenney, S. Expression of the Epstein-Barr Virus Immediate early genes in Drosophila: A study of viral pathogenesis. In preparation