
Chia-Chi Chuang came to UNCG on a graduate fellowship after reading about the work of nutrition professor Dr. Michael McIntosh. Since arriving on campus in 2007, she's made significant discoveries related to obesity and diabetes.
Chia-Chi Chuang, a fourth year doctoral student in nutrition, recently discovered another important factor in preventing the inflammation associated with obesity and insulin resistance. Chia-Chi's research findings, published in the Journal of Nutritional Biochemistry in 2010, confirmed the French paradox, which holds that consuming a diet containing grape products rich in phytochemicals like resveratrol helps minimize one's risk for obesity and diabetes. Now Chuang, who came to UNCG from Taipei on a graduate scholarship, has made a new discovery. Her latest study, published in the American Journal of Clinical Nutrition in 2010, compares the effectiveness of resveratrol to another plant compound, quercetin. Her findings suggest that quercetin, a phytochemical found in grapes, apples and onions, is as effective, if not more effective, than resveratrol in preventing inflammation associated with obesity and type 2 diabetes. Currently, Chuang is conducting a study with obese mice fed a high-fat diet to determine the extent to which grape powder rich in quercetin reduces chronic inflammation and diabetes. These studies are expected to increase research-based evidence supporting the consumption of grapes and grape products to combat obesity-mediated chronic inflammation.