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Dr. Deborah E. Kipp

233 Stone Building
P.O. Box 26170
University of North Carolina at Greensboro
Greensboro, NC 27402-6170
Phone (336)334-5733   Fax (336)334-5089
e-mail: d_kipp@uncg.edu

B.S. Nutrition, Arizona State University, Tempe, AZ 1975
Dietetic Internship, Miami Valley Hospital, Dayton, OH  1976
Ph.D. Nutrition, Cornell University, Ithaca, NY 1984


RESEARCH INTERESTS

Ongoing research focuses on the role of nutrients (ascorbic acid, iron) and hormones (prolactin) in regulating collagen production and key aspects of bone remodeling, using animal models and cell culture.

CURRENT RESEARCH

Maternal ascorbic acid intake and fetal skeletal development in the guinea pig in vivo; ascorbic acid effects on in vitro phenotypic development and on constitutive and endotoxin-induced stimulation of cytokines by osteoblast-like cells derived from fetal rat calvariae; prolactin effects on the rat skeleton; iron deficiency anemia on bone development and remodeling in the rat.

RECENT PUBLICATIONS

Peterkofsky, B., Gosiewska, A., Kipp, D.E., Shah, V. and Wilson, S. Induced insulin-like growth factor binding proteins (IGFBPS) 1 and 2 in sera from vitamin C-deficient or fasted guinea pigs inhibit IGF-1dependent fractions in cultured cells. Growth Factors 10: 229-241, 1994.

Kipp, D.E., Gosiewska, A., Wilson, S. and Peterkofsky, B. Differential regulation of collagen gene expression in granulation tissue and non-repair connective tissues in vitamin C-deficient guinea pigs. Wound Rep. Reg. 3: 192-203, 1995.

Kipp, D.E., McElvain, M., Kimmel, D.B., Akhter, M.P., Robinson, R.G. and Lukert, B.P. Scurvy results in decreased collagen synthesis and bone density in the guinea pig animal model. Bone 18: 281-288, 1996.

Kipp, D.E., Grey, C.E., McElvain, ME., Kimmel, D.B., Robinson, R.G., and Lukert, B.P. Long-term low ascorbic acid intake reduces bone mass in guinea pigs. J. Nutr. 126: 2044-2049, 1996.

Kipp, D.E., Radel, J.D. and Hogue, J.A. The internet and the nutritional scientist. Am. J. Clin. Nutr. 64: 659-662, 1996.

Pate, S.K., Lukert, B.P. and Kipp, D.E. Tissue vitamin C levels of guinea pig offspring are influenced by maternal vitamin C intake during pregnancy. J. Nutr. Biochem. 7: 524-528, 1996.

Kipp, D.E. Reflections on teaching graduate students how to use and publish nutrition information on the world wide web. J. Nutr. Ed. 28: 308-312, 1996.

Kipp, D.E. Developing interactive computerized modules, accessible on the World Wide Web, for medical students. Topics Clin. Nutr. 12: 38-44, 1997.

Fox-Bacon, C., McCamman, S., Therou, L., Moore, W. and Kipp, D. E. Maternal PKU and breastfeeding: Case report of identical twins. Clin. Pediatr. 36: 539-542, 1997.

Lukert, B.P., Kipp, D, and Broy, S. Management of glucocorticoid-induced osteoporosis. First, do no harm. (Letter to the editor). Arthritis Rheum. 8: 1548, 1997.

Kipp, D.E., McElvain, M.E., Latif, S., Stancliffe, H., Lukert, B.P., and Kimmel, D.B. Rapid reversal of bone abnormalities after ascorbic acid reintroduction to the scorbutic guinea pig. (submitted, Bone)

Kipp, D.E., Mohankumar, P.S., Voogt, J.L. and Kimmel, D.B. Bone status in ovariectomized adult rats with hyperprolactinemia. (submitted, Calcif. Tissue Int.)

Fox, C., Marquis, J. and Kipp, D.E. Nutrition factors affecting serum phenylalanine concentration during pregnancy for identical twins. (submitted, Acta Paediatr.)

Mandagere, K.A., Taylor, C.C., Lukert, B.P., and Kipp, D.E. Prolactin stimulates in vitro growth and inhibits function of fetal rat osteoblast-like cells. (submitted, Endocrinology)

Taylor, C.C., Hiatt, J.A., Lukert, B.P., and Kipp, D.E. Ascorbic acid inhibits cytokine production and secretion by rat fetal osteoblast-like cells cultured in vitro. (submitted, Endocrinology)


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The University of North Carolina
at Greensboro

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