Department of Nutrition

  1. Home
  2. About Nutrition
  3. Study Abroad Opportunities (pdf file)
  4. Undergraduate Program Info.
  5. Graduate Program Info.
  6. Dietetic Internship
  7. Faculty
    1. Lynda Brown, Ph.D.
    2. Keith Erikson, Ph.D.
    3. Lauren Haldeman, Ph.D.
    4. Deborah E. Kipp, Ph.D., R.D.
    5. George Loo, Ph.D.
    6. Cheryl Ann Lovelady, Ph.D., R.D.
    7. Michael K. McIntosh, Ph.D., R.D.
    8. Ron F. Morrison, Ph.D.
    9. Suzanne E. Rhodes, M.S.
    10. Margaret R. Savoca, Ph.D.
    11. Amy Strickland, M.S., R.D.
    12. Martha L. Taylor-Hawkins, Ph.D., R.D.
    13. Rosemary C. Wander, Ph.D.
  8. Research
  9. Student Organizations
    1. The Nutrition Club
    2. Nutrition Graduate Student Association
  10. Career Options
  11. Important Links
  12. Seminar Schedule (pdf file)
  13. Accomplishments (pdf file)
  14. Nutrition focus at the NC Research Campus located in Kannapolis, NC
  15. HES

Lynda M. Brown, Ph.D.

Assistant Professor
Office: 336-256-0320
email: lmbrown6@uncg.edu

Education and Positions

- Assistant Professor, Dept. of Nutrition, University of North Carolina at Greensboro, 2006-present
- Adjunct Assistant Professor, Dept. of Nutrition, University of North Carolina at Greensboro, 2005-2006
- Postdoctoral Fellow, Obesity Research Center, Genome Research Institute, University of Cincinnati College of Medicine, 2003-2006
- Ph.D., Nutrition, University of Maryland, College Park, 2003

Research Interest   (For more information)

- Determine the role of estrogen in determining visceral fat as well as the brain's sensitivity to leptin in middle-aged female rats.
- Central leptin/insulin resistance and their importance in the metabolic syndrome.
- Animal models of obesity including Long-Evans rats, fatty Zucker rats and diet-induced obese rats.
- Establish novel techniques to explore the association between aging, estrogen levels and body fat as female rats end their reproductive capacity (mimicking menopause in women).

Current Research

- The importance of sex hormones in body fat distribution and energy homeostasis.
- The role of sex hormones in central insulin and leptin resistance and increased visceral fat associated with aging.
- Central insulin resistance in animals maintained on low- and high-fat diets.
- The use of novel therapeutic compounds to reveal the cellular mechanisms of central insulin and leptin sensitivity.

Selected Publications

- Castonguay TW & LM Brown. Effects of food deprivation, starvation and exercise on dietary selection in the rat. In: HR Berthoud & RJ Seeley (eds.) Metabolically Driven Changes in Macronutrient Selection. CRC Press, Boca Raton, pp 219 - 232, 2000.

- Castonguay TW, S Beaulieu, RL Eskay, N Barden, K Kamara, S Khozin, L Lustberg & LM Brown. The effects of adrenalectomy and aldosterone replacement in transgenic mice expressing antisense RNA to the type-2 glucocorticoid receptor. Physiology and Behavior 77:417-423, 2002.

- Haggans CJ, KS Regan, LM Brown, C Wang, J Krebs-Smith, PM Coates & CA Swanson. Computer access to research on dietary supplements (CARDS), a database of federally funded dietary supplement research. Journal of Nutrition, 135: 1796-1799, 2005.

- Clegg DJ, LM Brown, SC Woods & SC Benoit. Gonadal hormones determine sensitivity to central leptin and insulin. Diabetes, Apr;55(4):978-87, 2006.

- Brown LM, DJ Clegg & SC Woods. Intraventricular insulin and leptin reduce food intake and body weight in C57BL/6J mice. Physiology and Behavior Dec; 89(5):687-691, 2006.

- Brown LM, SC Woods & DJ Clegg. Food intake and plasma ghrelin levels following central ghrelin administration in fatty Zucker rats. Peptides Mar 28(3):612-616, 2007.

- Clegg DJ, LM Brown, CJ Kemp, AD Strader, SC Benoit, SC Woods, M Mangiaracina & N Geary. Estradiol-decrease in the orexigenic potency of ghrelin in female rats. Diabetes Apr;56(4):1051-8, 2007.

- Gotoh K, MD Wortman, SC Benoit, DJ Clegg, LM Brown, D D'Alessio, P Tso, RJ Seeley & SC Woods. Consumption of a high fat diet induces central insulin resistance independent of obesity. Submitted to Endocrinology.

- Brown LM, CT Hansen, AF Huberty & TW Castonguay. Genetic background and adrenalectomy alter Neuropeptide Y5 expression and carcass composition in corpulent rats. Submitted to Physiology and Behavior.

TOP

 

Page updated: 16-Sep-2007

Accessibility Policy

Department of Nutrition
The University of North Carolina at Greensboro
PO Box 26170
Greensboro, NC 27402-6170
VOICE 336.334.5313
EMAIL nutrition@uncg.edu