Publications
Paul Anthony Steimle
Assistant Professor
Department of Biology
312 Eberhart Building
University of North Carolina at Greensboro
Greensboro, NC 27402
p_steiml@uncg.edu

PUBLICATIONS: Papers are listed with most recent publications first

  1. Russ, M., Croft, D., Ali, O., Martinez, R. and Steimle, P.A. (2005) Myosin Heavy Chain Kinase A from Dictyostelium Possesses a Novel Actin Binding Domain that Cross-Links Actin Filaments. Submitted and In revision.

  2. Steimle, P.A., Fulcher, K.F., Patel, Y.M. (2005) A novel role for myosin II in insulin-stimulated glucose uptake in 3T3-L1 adipocytes.  Biochemical and Biophysical Research Communications.  331(4): 1560-1565. [Ref link]

  3. Egelhoff, T.T., Croft, D., Steimle, P.A. (2005) Actin-Activation of Myosin Heavy Chain Kinase A in Dictyostelium: A biochemical mechanism for the spatial regulation of myosin II filament disassembly.  Journal of Biological Chemistry. 280:2879 – 2887. [Ref link]
  4. Steimle, P.A., Licate, L., Côté, G.P., Egelhoff, T.T. (2002) Lamellipodial localization of  Dictyostelium myosin heavy chain kinase A is mediated via F-actin binding by the coiled-coil domain. FEBS Letters. 516:58-62. [Ref link]

  5. Steimle, P.A., Yumura, S., Côté, G.P., Medley, Q.G., Polyakov, M., Leppert, B., Egelhoff, T.T. (2001) Recruitment of a myosin heavy chain kinase to actin-rich protrusions in Dictyostelium.  Current Biology. 11:708-713. [Ref link]

  6. Jarroll, E.L., Macechko, P.T., Steimle, P.A., Bulik, D., Karr, C.D., van Keulen, H., Paget, T.A., Gerwig, G., Kamerling, J., Vliegenthart, J., Erlandsen, S. (2001) Regulation of carbohydrate metabolism during Giardia encystment. Journal of Eukaryotic Microbiology. 48:22-26. [Ref link]

  7. Luo, X., Crawley, S.W., Steimle, P.A., Egelhoff, T.T., Côté, G. P. (2001) Specific phosphorylation of threonine by the Dictyostelium myosin II heavy chain kinase family.  Journal of Biological Chemistry. 276: 17836-17843. [Ref link]

  8. Steimle, P.A., Licate, L., Naismith, T., Egelhoff, T.T.  (2000) WD-Repeat domains target Dictyostelium myosin heavy chain kinase activities by binding directly to myosin II.  Journal of Biological Chemistry.  276:6853-6860. [Ref link]

  9. Steimle, P.A., Hoffert, J.D., Adey, N.B, Craig, S.W. (1999) Polyphosphoinositides inhibit the interaction of vinculin with actin filaments.  Journal of Biological Chemistry. 274:18414-18420. [Ref link]

  10. Van Keulen, H., Steimle, P.A., Boroviak, R.K., Bulik, D.A., Jarroll, E.L. (1998) Cloning of two putative Giardia lamblia glucosamine 6-phosphate isomerase genes only one of which is transcriptionally activated during encystment. Journal of Eukaryotic Microbiology. 45(6): 637-642. [Ref link]

  11. Jarroll, E.L., Macechko, P.T., Steimle, P.A., Lindmark, D.G., and Erlandsen, S.L. (1994) Enzymes of galactosamine synthesis in encysting Giardia are induced. In: Giardia: From Molecules to Disease. (Thompson, A., Reynoldson, J., and Lymbury, A., eds). CAB International, Oxon, U.K. pp. 198-199.

  12. Steimle, P.A., Lindmark, D.E., Jarroll, E.L. (1996) Purification and characterization of encystment-induced glucosamine 6-phosphate isomerase in Giardia. Molecular and Biochemical Parasitology. 84:149-153. [Ref link]

  13. Macechko, P.T., Steimle, P.A., Lindmark, D.G., Erlandsen, S.L., Jarroll, E.L. (1992) Galactosamine synthesizing enzymes are induced when Giardia encyst. Molecular and Biochemical Parasitology. 56:301-310. [Ref link]

Recent Meeting Abstracts:

  • D. Croft, M. Sharp, P. Brake, R. Martinez, P. Steimle. (2004) Studies of the Actin-Binding and Cellular Translocation Activities of Myosin Heavy Chain Kinase A from Dictyostelium Reveal a Coiled-Coil Domain with Multiple Functions. 44th Annual Meeting of the American Society for Cell Biology. December 4 - 8, 2004. Washington, DC. 
  • D. Croft, K. LaPoint, T. T. Egelhoff, P. A. Steimle. (2003)  Dictyostelium Myosin Heavy Chain Kinase A is Activated by a Direct Interaction with Actin Filaments.  43rd  Annual Meeting of the American Society for Cell Biology. December 13 - 17, 2003.
  • Croft, D., Tibaquiara, L.I., Egelhoff, T.T., Steimle, P.A. (2002)  Dictyostelium myosin heavy chain kinase A localizes to actin-rich cortical structures via f-actin binding by its coiled-coil domain.  December 14 - 18, 2002. 41st Annual Meeting of the American Society for Cell Biology. San Francisco, CA.

 

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