Shyam Aravamudham

Professor, Nanoengineering

Dean's Office - Nanoscience and Nanoengineering

Email Address: s_aravam@uncg.edu

Phone: 336.285.2856

Research

Aravamudhan Lab works at the intersection of materials, devices, biology, and advanced manufacturing. Our research advances materials, interfaces, and devices that bridge fundamental micro and nanoengineering with scalable technologies for semiconductors, biomedicine, energy, quantum systems, and environmental health. The lab focuses on atomic- and nanoscale control of materials, their integration into functional platforms, and student training across fabrication, characterization, modeling, and application-driven research. A unifying theme of the Aravamudhan Lab is the development of materials-to-device and materials-to-bio platforms.

Current Research Areas

  • Two-Dimensional Materials and Nanoelectronics – Wafer-scale synthesis, characterization, defect engineering, and interface control in 2D materials.
  • Atomic Layer Deposition and Thin-Film Materials – ALD and PVD synthesis of transition-metal oxides, nitrides, and 2D materials for microelectronics, catalysis, energy, and quantum applications.
  • Nanobioelectronics and Regenerative Engineering – Nanoelectrode-based electrical stimulation platforms and regenerative engineering applications.
  • Biosensing and Diagnostics – Nanostructured platforms for small-molecule detection and biomarker sensing.
  • Nanotoxicology and Semiconductor Environmental Health and Safety – Biological and environmental interactions of engineered and incidental nanomaterials, including materials relevant to semiconductor processing.
  • MEMS, Microfluidics, and Micro/Nanosystems – Microfluidic sensors, nanoscale interfaces, and integrated device platforms.

Publications

  • Zablon, F. M., Dellinger, K., & Aravamudhan, S. “Advances in MoS₂-Au Nanostructured Platforms for Cancer-Derived miRNA Detection.” Advanced Materials Interfaces, 2026.
  • Zablon, F. M., Pathiraja, G., Dellinger, K., & Aravamudhan, S. “In-situ growth of heterogeneous Au on MoS₂ nanosheets for SERS detection of breast cancer-derived miR-210-3p and miR-9-3p.” Scientific Reports, 2026.
  • Nalawade, S., Kim, R. S., Mahl, J., Cherono, S., Chris-Okoro, I., Craciun, V., et al., & Aravamudhan, S. “Phase Transformation and Water Adsorption Behavior of As-Deposited and Annealed Ru Metal Thin Films Prepared by Atomic Layer Deposition.” Advanced Materials Interfaces, 13(1), e00689, 2026.
  • Zablon, F. M., Khan, M. A. R., Ignatova, T., Dellinger, K., & Aravamudhan, S. “Physical Adsorption-Driven Assembly of Au-Locked Nucleic Acid Probes on MoS₂ Nanosheets for SERS-Based Detection of microRNAs.” Advanced Materials Interfaces, 12(23), 2025.
  • Hossen, M. F., Shendokar, S., & Aravamudhan, S. “Quantitative Defect Analysis in CVD-Grown Monolayer MoS₂ via In-Plane Raman Vibration.” Nano Select, 6(4), e202400103, 2025.
  • Chris-Okoro, I., Cherono, S., Akande, W., Nalawade, S., Liu, M., Martin, C., et al. “Optical and Plasmonic Properties of High-Electron-Density Epitaxial and Oxidative Controlled Titanium Nitride Thin Films.” The Journal of Physical Chemistry C, 129(7), 3762, 2025.
  • Razgaleh, S. A., & Aravamudhan, S. “Enhanced Thermal Management in Microelectronics Packaging With 2D h-BN Nanocomposite Underfills.” Nano Select, 6(2), e202400073, 2025.
  • Williams, W. A., Nowlin, K., Ayodele, O., & Aravamudhan, S. “Application of MATLAB and SAS Viya AI Models towards the Elucidation of Potential Microplastics in the Neuse River Basin.” Microplastics and Nanoplastics, 4(1), 1–20, 2024.
  • Shendokar, S., Hossen, M. F., & Aravamudhan, S. “Wafer-Scale ALD Synthesis of MoO₃ Sulfurized to MoS₂.” Crystals, 14(8), 673, 2024.
  • Hossen, M. F., Shendokar, S., & Aravamudhan, S. “Defects and Defect Engineering of Two-Dimensional Transition Metal Dichalcogenide Materials.” Nanomaterials, 14(5), 410, 2024

Funding Sources

  • National Science Foundation (NSF)
  • National Institute of Health (NIH)/RTI International
  • Semiconductor Research Corporation (SRC)
  • North Carolina Biotechnology Center (NCBC)
  • University of North Carolina General Administration (UNC-GA) ROI

Graduate Students

Current Graduate Students and Projects

  • Smith Woosley – Functional 3D Printing
  • Sara Abbasi – Hexagonal Boron Nitride in Microelectronics Packaging
  • Steven Crawford – EHS of Engineered and Transformed Nanoparticles
  • Hamed Ghazizadeh – Role of Mechanical Stimuli on Mammalian Cell Function
  • Frederick Aryeetey – Controlled Defect Generation and Doping of 2D MoS2
  • Qassim Dirar – co-advising with Dr. Yeoheung Yun, Bioengineering, NCA&T
  • Sheikh Saudi – co-advising with Dr. Narayan Bhattarai, Bioengineering, NCA&T
  • Sahil Tahiliani – Transformation and EHS of CMP Slurries in Semiconductor Manufacturing
  • Sharmista Prattipati – EHS of Indium and its Compounds in Semiconductor Manufacturing
  • Minakshi Molawade – Direct Printing of MoS2 Structures and Devices

Outreach