Education
B.S. Biological Sciences, Sao Paulo State University
M.S. Physiological Sciences, Federal University of Sao Carlos
Ph.D Applied Sciences, William & Mary
Courses Taught
- BIO 111L: Principals of General Biology (Lab)
- BIO 271L: Human Anatomy (Lab)
- BIO 277L: Human Physiology (Lab)
Research
My research interest include understanding the neural mechanisms underlying breathing control, specifically looking at ion channels and neuron populations and their role in the respiratory function. Moreover, my research also seeks to investigate how early-life events, such as gene deletion and use of drugs during pregnancy, affect the respiratory function at the brain and lung levels.
Selected Publications
da Silva Junior, C.A., Grover, C.J., Picardo, M.C.D., Del Negro, C.A. (2023). Role of NaV1.6-mediated persistent sodium current and bursting-pacemaker properties in breathing rhythm generation. Cell Reports. https://10.1016/j.celrep.2023.113000.
da Silva Junior, C.A., Marques, D.A., Patrone, L.G.A., Biancardi, V., Bícego, K.C., Gargaglioni, L.H. (2023). Intra-uterine diazepam exposure decreases the number of catecholaminergic and serotoninergic neurons of neonate rats. Neuroscience letters, 795. https://doi.org/10.1016/j.neulet.2022.137014.
da Silva Junior, C.A., Patrone, L.G.A., Biancardi, V., Vilela-Costa, H.H., Marques, D.A., Cristina-Silva, C., da Costa Silva, K.S., Bícego, K.C., Szawka, R.E., Gargaglioni, L.H. (2022). Sexually dimorphic effects of prenatal diazepam exposure on respiratory control and the monoaminergic system of neonate and young rats. Pflugers Arch. 474 (11), 1185-1200. https://doi.org/10.1007/s00424-022-02730-7.
da Silva Junior, C.A., Picardo, M.C., Del Negro, C. (2022). RNA interference via shRNA decreases the number of transcripts of Scn8a in glutamatergic interneurons in the preBötC. The FASEB Journal. https://doi.org/10.1096/fasebj.2022.36.S1.R2948.
da Silva Junior, C.A., Biancardi, V., Patrone, L.G.A., Bícego, K.C. and Gargaglioni, L.H. (2020). Intra-uterine exposure to Diazepam decrease the ventilatory response and impairs the motor behavior of males and females at post-natal life. The FASEB Journal, 34. https://doi.org/10.1096/fasebj.2020.34.s1.06981.
Leirão, I. P., Silva, C. A. Jr, Gargaglioni, L. H., da Silva, G. (2018). Hypercapnia-induced active expiration increases in sleep and enhances ventilation in unanaesthetized rats. The Journal of Physiology, 596 (15), 3271–3283. https://doi.org/10.1113/JP274726.
Augusto, T. G. da S., Silva Junior, C. A. (2020). A trajetória do sangue no corpo humano: a história da ciência na formação continuada de professores de biologia. [EN: The path of blood in the human body: history of science in the training of in-service biology teachers]. Revista Brasileira de História Da Ciência, 13 (2), p. 250-260. https://doi.org/10.53727/rbhc.v13i2.37.
